Endothelial pas domain protein 1 epas1

Author: wmqe

August undefined, 2024

WebOrthologous to human EPAS1 (endothelial PAS domain protein 1). [provided by Alliance of Genome Resources, Apr 2024] Other designations. endothelial PAS domain-containing protein 1, EPAS-1, HIF-2-alpha, HIF2-alpha, hypoxia inducible factor 2, alpha subunit, hypoxia inducible factor 2a, hypoxia-inducible factor 2-alpha. WebJun 10, 2004 · Endothelial PAS domain protein 1 (EPAS1) is a member of basic-helix-loop-helix/PAS domain containing transcription factor family and has a high homology to HIF-1α, thus also termed HIF-2α. 2,3 Like HIF-1α, the EPAS1 protein is stabilized during hypoxia and forms a heterodimer with aryl hydrocarbon receptor nuclear translocator …

Identification of novel mutations and functional impacts of EPAS1 …

WebMar 21, 2024 · EPAS1 (Endothelial PAS Domain Protein 1) is a Protein Coding gene. Diseases associated with EPAS1 include Erythrocytosis, Familial, 4 and Multiple … WebEndothelial PAS domain protein 1 (EPAS1) is a hypoxia-inducible transcription factor and plays an important role in the catecholamine and mitochondrial homeostasis, in the control of cardiac output and erythropoietin regulation. Recently, Voisin et al. have investigated the frequencies of the EPAS1 (also known as HIF2A; location: 2p21-p16) gene ... kubota t1400 lawn tractor parts

Endothelial PAS Domain Protein 1 Gene Promotes …

WebIn this study, investigation of the role of the endothelial PAS domain-containing protein 1 (EPAS1), a regulatory α subunit of the hypoxia-inducible factor complex, during angiotensin II-induced hypertensive nephropathy provided novel insights into FSGS pathogenesis in the absence of a primary podocyte abnormality. WebSep 11, 2024 · Abstract. Endothelial PAS domain-containing protein 1 (EPAS1) is an angiogenic factor and its implications have been reported in many cancers but not in esophageal squamous cell carcinoma (ESCC). Herein, we aim to examine the genetic and molecular alterations, clinical implications, and functional roles of EPAS1 in ESCC. Web丁香通为您提供人EPAS1内皮细胞PA商品详情介绍：价格：￥11，货号：NDC-EKX-UF5FOY-96，品牌：Nordic BioSite，详见丁香通人EPAS1内皮细胞PA商品详情页； ... (Endothelial PAS domain-containing protein 1) ELISA Kit ... kubota t2290 lawn tractor reviews

EPAS1 Gain-of-Function Mutation Contributes to High-Altitude …

Endothelial PAS Domain Protein 1 Gene Promotes …

WebEndothelial PAS domain-containing protein 1 (EPAS1) has implications in many cancers. However, the molecular behaviours, functional roles and mutational status of EPAS1 … WebFeb 12, 2024 · EPAS1 endothelial PAS domain protein 1 Gene ID: 2034, updated on 27-Nov-2024 Gene type: protein coding Also known as: HLF; MOP2; ECYT4; HIF2A; … kubota t1880 lawn tractorWebOct 24, 2024 · Recent studies have demonstrated that mutations in endothelial PAS domain-containing protein 1 (EPAS1) is associated with manifestations of phaeochromocytomas and paragangliomas [1,9,12,13,14]. EPAS1, also known as HIF-2α, encodes for one of the hypoxia inducible factor (HIF) family members, which is involved … kubota telescopic lower link/stabilizer kit

"WebJul 4, 2024 · We identify that the endothelial PAS domain protein 1 gene (EPAS1, also HIF2A) shows the strongest signature for positive selection in the Tibetan horse genome. Two missense mutations at this locus appear strongly associated with blood physiological parameters facilitating blood circulation as well as oxygen transportation and … " - Endothelial pas domain protein 1 epas1

Endothelial pas domain protein 1 epas1

WebSep 5, 2024 · Tian et al. (1997)suggested that EPAS1 may represent an important regulator of vascularization, perhaps involving the regulation of endothelial cell gene expression … WebEndothelial PAS domain protein 1 gene (EPAS1) is a member of the HIF gene family. This gene encodes a transcription factor subunit that is involved in the induction of oxygen-regulated genes. Several studies have demonstrated that a mutation in EPAS1 could affect oxygen sensing, polycythemia, and hemoglobin level. However, whether EPAS1 …

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WebEPAS1 (Endothelial PAS Domain Protein 1) Orchestrates Transactivation of Endothelial ICAM1 (Intercellular Adhesion Molecule 1) by Small Nucleolar RNA Host Gene 5 … WebMar 9, 2024 · Epas1 endothelial PAS domain protein 1 [ Mus musculus (house mouse) ] Gene ID: 13819, updated on 9-Mar-2024 Download Datasets Summary Official Symbol …

WebSeveral results point to HIF-1α, 11-13 but mouse Hif-2α (also known as endothelial PAS domain protein 1 [Epas1] or Hif-1α–like factor [Hlf]) has been implicated as the principal regulator of ... WebHIF-2α (also known as endothelial PAS domain protein 1, EPAS1) has been shown to share transcriptional target genes with HIF-1α such as VEGF, tyrosine kinase receptor with immunoglobulin and epidermal growth factor homology 2 (Tie2), Ang-2 and fms-like tyrosine kinase 1 (Flt-1), and also regulated by cellular oxygen tension.

WebNM_001430.5(EPAS1):c.*833G>A AND Erythrocytosis, familial, 4 Clinical significance: Uncertain significance (Last evaluated: Jan 12, 2024) Review status: 1 star out of maximum of 4 stars WebSep 11, 2024 · Endothelial PAS domain-containing protein 1 (EPAS1) is an angiogenic factor and its implications have been reported in many cancers but not in esophageal squamous cell carcinoma (ESCC). …

WebJul 3, 2003 · Protein Endothelial PAS domain-containing protein 1 Gene EPAS1 Status UniProtKB reviewed (Swiss-Prot) Organism Homo sapiens (Human) Amino acids 870 …

WebOct 28, 2010 · But in the other two studies (Beall et al. 2010; Yi et al. 2010), EPAS1 (endothelial PAS domain protein 1; also known as hypoxia-inducible factor-2α [HIF-2α]) was considered the candidate gene that has undergone positive … kubota tiller attachment for tractorWebAug 30, 2024 · EPAS1 (endothelial PAS domain protein 1), also referred to as HIF-2α, is considered the master regulator of hypoxia stimuli in endothelial cells. 15, 16 Recently, … kubota track loader discountsWebEPAS1 gene endothelial PAS domain protein 1 Normal Function The EPAS1 gene, often known as HIF2A, provides instructions for making a protein called hypoxia-inducible factor 2-alpha (HIF-2α). This protein is one part (subunit) of a larger protein complex called HIF, which plays a critical role in the body's ability to adapt to changing oxygen ... kubota tire chains 26x12 12WebApr 9, 2024 · Our results showed that ZnO-NR treatments increased cell death through ROS accumulation, HIF-1α and endothelial PAS domain protein 1 (EPAS1) activation, and induction of autophagy and mitophagy in both cell lines. These results, while on one side, confirmed that ZnO-NRs can be used to reduce cancer growth, on the other side, raised … kubota thailand websiteWebEndothelial PAS domain protein 1 activates the inflammatory response in the intestinal epithelium to promote colitis in mice Authors Xiang Xue 1 , Sadeesh Ramakrishnan , Erik … kubota t1400h lawn tractor partsWebMar 21, 2024 · EPAS1 (Endothelial PAS Domain Protein 1) Orchestrates Transactivation of Endothelial ICAM1 (Intercellular Adhesion Molecule 1) by Small Nucleolar RNA Host … kubota thunder bay hoursWebthelial PAS domain protein 1 (EPAS1) is a member of basic-helix–loop–helix/PAS domain containing transcription factor family and has a high homology to HIF-1 , thus also termed HIF-2 .2,3 Like HIF-1 , the EPAS1 protein is stabi-lized during hypoxia and forms a heterodimer with aryl hydrocarbon receptor nuclear translocator (ARNT) and trans- kubota toy tractors with loaders