Cthrc1 gene

Author: cdjv

August undefined, 2024

WebOct 8, 2012 · Generation of Cthrc1 null mice. (A) Cthrc1 gene targeting schematic showing replacement of exons 2-4 with a PGK-neo cassette. (B) Embryonic stem cell targeting with Southern blot analysis of ... WebBackground: We discovered the gene Collagen Triple Helix Repeat Containing 1 (Cthrc1) and reported its developmental expression and induction in adventitial cells of injured …

CTHRC1 promotes liver metastasis by reshaping …

WebMar 20, 2024 · Correlations between CTHRC1 gene expression and clinicopathological factors were analyzed using gene expression data from UALCAN databases. Then, we searched the GEPIA database to evaluate the association of CTHRC1 gene expression with clinical outcomes. The cBioPortal database was used to analyze CTHRC1 genetic … WebELISA Kits by Target . ELISA (enzyme-linked immunosorbent assay) is a plate-based technique for detection and quantification of antibodies or proteins such as cytokines, chemokines, growth factors, hormones, and intracellular phosphorylated proteins. porsche boxster 981 usata

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WebMar 20, 2024 · The collagen triple helix repeat containing 1 (CTHRC1) gene is located on human chromosome 8q22.3 and was initially identified in balloon injury and normal rat … WebSep 23, 2024 · Through bioinformatics analyses and experiments, we confirmed that CTHRC1 is highly expressed in tissues and hepatoma cell lines. High expression of the CTHRC1 gene is associated with poor prognosis. Collectively, the results of the present study indicated that CTHRC1 may serve as a prognostic biomarker for HCC. Webby Gene › by Protein › CTHRC1 Antibodies; CTHRC1 Antibodies . Antibodies that detect CTHRC1 can be used in several scientific applications, including Western Blot, Immunohistochemistry, ELISA, Immunocytochemistry and Immunoprecipitation. These antibodies target CTHRC1 in Human, Mouse and Rat samples. Our CTHRC1 polyclonal, … sharp trophies by mack shelbyville in

CTHRC1 is a prognosis-related biomarker correlated with immune ...

Human CTHRC1 ELISA Kit (ab274399) Abcam

WebDec 22, 2024 · The X-axis represent ligand and receptor pairs, with the first gene expressed on F13-Act-CTHRC1 cells and second gene expressed on the interacting cell types denoted in the Y-axis. Red: upregulated gene in tumor bulk RNA-seq. Blue: downregulated in tumor bulk (none present). WebGene view. The gene view histogram is a graphical view of mutations across CTHRC1. These mutations are displayed at the amino acid level across the full length of the gene … sharp tree farmhttp://www.informatics.jax.org/marker/MGI:1915838 porsche boxster 986 backup cameras

"WebAug 12, 2024 · Collagen triple helix repeat containing-1 (CTHRC1) has been identified as cancer-related protein. CTHRC1 expresses mainly in adventitial fibroblasts and … " - Cthrc1 gene

Cthrc1 gene

WebSep 21, 2011 · Orloff et al. (2011) identified a germline 131A-C transversion in exon 1 of the CTHRC1 gene, resulting in a gln44-to-pro (Q44P) substitution, in 1 (1.1%) of 116 patients of European descent with Barrett esophagus and/or esophageal adenocarcinoma ().The mutation was not found in 125 controls. The same mutation was found in 1 (1.7%) of 58 … WebJan 29, 2013 · Colorectal cancer (CRC) patients with peritoneal carcinomatosis (PC) have a poor prognosis. Over the last decade, increasing evidence has suggested that the Collagen Triple Helix Repeat Containing 1 (CTHRC1) gene is involved in cancer progression and invasion. In this study, we investigated the expression of CTHRC1 in CRC and its …

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WebTreatment of cholestatic fibrosis by altering gene expression of Cthrc1: Implications for autoimmune and non-autoimmune liver disease Author links open overlay panel Zhaolian Bian a 1 , Qi Miao a 1 , Wei Zhong a 1 , Haiyan Zhang a , Qixia Wang a , Yanshen Peng a , Xiaoyu Chen a , Canjie Guo a , Li Shen a , Fan Yang a , Jie Xu a , Dekai Qiu a ... WebAug 7, 2024 · We reveal gene expression signatures that demarcate fibroblasts from mural cells and provide molecular signatures for cell subtype identification. ... C1qtnf3, and Cthrc1) their distribution in ...

WebDec 1, 2001 · Disease susceptibility is associated with variants affecting the gene represented in this entry Description A condition characterized by a metaplastic … WebMar 21, 2024 · CTHRC1 (Collagen Triple Helix Repeat Containing 1) is a Protein Coding gene. Diseases associated with CTHRC1 include Barrett Esophagus and Adenocarcinoma . Among its related pathways are Wnt …

WebFeb 8, 2024 · Introduction. The collagen triple helix repeat containing 1 (Cthrc1) gene was first reported by the Lindner laboratory in a screen for genes differentially expressed upon major damage to arteries in rats (Pyagay et al. 2005).Cthrc1 was highly induced in injured arteries, with expression subsiding upon healing (Pyagay et al. 2005; LeClair et … WebFeb 8, 2024 · We assessed the cause of elevated CTHRC1 levels. DNA methylation, gene mutation, CNV was critically involved in genetic and epigenetic regulation and were …

WebMar 21, 2024 · CTHRC1 serves as a pro-metastatic gene that contributes to NSCLC invasion and metastasis, which are mediated by upregulated MMP7 and MMP9 …

WebOct 26, 2024 · The function of collagen triple helix repeat containing 1 (CTHRC1) as an oncogene has been reported in a growing number of publications. Bioinformatics methods represent a beneficial approach to examine the mechanism and function of the CTHRC1 gene in the disease process of cancers from a pan-cancer perspective. In this study, … sharp turn crossword puzzle clueWebOct 8, 2012 · Background We discovered the gene Collagen Triple Helix Repeat Containing 1 (Cthrc1) and reported its developmental expression and induction in adventitial cells of injured arteries and dermal cells of skin wounds. The role of Cthrc1 in normal adult tissues has not yet been determined. Methodology/Principal Findings We … sharptronics coimbatoreWebAug 30, 2024 · Gene ID: 68588, updated on 30-Aug-2024. Summary Other designations. collagen triple helix repeat-containing protein 1. GeneRIFs: Gene References Into Functions. GPR180 is a component of TGFbeta signalling that promotes thermogenic adipocyte function and mediates the metabolic effects of the adipocyte-secreted factor … sharp tse sd cardWebAug 30, 2024 · The occurence frequency of CTHRC1 gene is higher in multiple Wnt signaling pathway associated with enrichment classes. Furthemore, CTHRC1 gene is positively correlated with ANOS1. This implies that CTHRC1 probably plays an important role in the gene function/process of ANOS1. Many studies have investigated the role of … sharp tub refinishingWebSep 25, 2024 · Collagen triple helix repeat containing 1, a novel secreted protein in injured and diseased arteries, inhibits collagen expression and promotes cell migration. Circ … sharp tumble dryers reviewsWebSep 9, 2008 · Methodology/Principal Findings. We identified collagen triple helix repeat containing-1 (Cthrc1) as a downstream target of bone morphogenetic protein-2 (BMP2) in osteochondroprogenitor-like cells by PCR-based suppression subtractive hybridization followed by differential hybridization, and found that Cthrc1 was expressed in bone … porsche boxster 987 brake light bulbWebGenomic Mutations. 2 involving Cthrc1. Incidental Mutations. Mutagenetix , APF. Find Mice (IMSR) 20 strains or lines available. Comparison Matrix. Gene Expression + Phenotype. … sharp turn 7 little words